About Shionogi

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Manufacturing

Shionogi strives constantly to provide the best possible products for people's health. We put priority on safety and environmental protection as well as product quality in our manufacturing activities.

  1. Pursuit of quality: Every product we make should be of the highest quality and give people peace of mind.
  2. Environmental protection: All living things on earth are entitled to good health.
  3. Securing employee safety: Employees should be able to work with confidence to provide the best possible products.

We contribute to pharmaceutical development through the functional development of technologies in manufacturing, formulation, packaging, and analysis as part of commercialization research that spans late drug discover stages through to commercial production. We also help to accelerate research and development through active involvement in the early stages of drug discovery.

  • We develop manufacturing methods to maintain suitable quality throughout product development, from early stage development through to commercial production, and from active ingredients through to formulation and packaging. Active pharmaceutical ingredients and drug products for clinical use are manufactured in facilities and under frameworks that conform with applicable domestic and overseas regulations.
  • To enhance quality and production efficiency in pharmaceutical manufacturing, we provide technology transfers and technological support to plants, affiliated subsidiaries and subcontractors.

Introduction to Production Facilities

Introduction to Production Facilities

Kuise Site

Kuise Site

The CMC Development Laboratories at our Kuise site conduct various research and pilot-scale manufacturing studies for the development of new chemical compounds that showcase Shionogi as a globally competitive company with strengths in the chemistry, manufacturing and control (CMC) function. The laboratories strive daily to develop higher-quality pharmaceuticals and to improve manufacturing methods for new active pharmaceutical ingredients and new drug products, packaging specifications, and manufacturing methods for clinical trial materials.

  • Pilot-scale manufacturing of active pharmaceutical ingredients and new drug products, including packaging
  • Manufacturing of active pharmaceutical ingredients and drug products for clinical use

Settsu Plant

Settsu Plant

Many of the preparations and sachets used for Shionogi's leading products, including solid preparations and injectables, are manufactured at the Settsu Plant. Automatic dust monitoring systems, automatic transport systems for raw materials and finished products, and automated production systems hold contamination to a minimum in the manufacturing of injectables and eye drops, which are subject to strict sterility and dust-free requirements. We have taken advantage of automation in every process; examples include the use of automatic weight-controlled tablet production systems and robots. Shionogi's original technology creates pharmaceuticals offering superior efficacy, safety, and stability and uniform quality.

  • Pharmaceutical manufacturing
  • Pharmaceutical sachet packaging

Kanegasaki Plant

Kanegasaki Plant

This facility is engaged in the entire spectrum of production, from bulk powder to preparations and packaging of in-house developed antibiotics, as well as pilot manufacturing of newly developed drugs (antibiotics). It is also engaged in the manufacturing of analgesics for cancer pain. The Kanegasaki Plant is a large-scale plant automated by computer control, and continues to produce high-quality products based on manufacturing technology and quality control that has passed strict inspections by domestic and overseas organizations, including the US Food and Drug Administration (FDA).

  • Bulk chemical manufacturing
  • Pharmaceutical manufacturing
  • Pharmaceutical sachet packaging
  • Antibiotic pilot manufacturing

Shionogi Pharma Chemicals Co., Ltd.

Shionogi Pharma Chemicals Co., Ltd.

The facility is a consolidated subsidiary of Shionogi established in August 1976 that is engaged in contracted manufacturing of pharmaceutical bulk chemicals. Shionogi Pharma Chemicals has installed GMP and quality assurance systems in compliance with global standards to accommodate the transfer of control of bulk chemical manufacturing from Shionogi and other companies, and has established a complete system covering the entire manufacturing process from development to manufacturing of general bulk chemicals.

  • Contracted manufacturing of pharmaceutical bulk chemicals
  • Contracted manufacturing of bulk chemicals for clinical study drugs

Shionogi Analysis Center Co., Ltd.

Shionogi Analysis Center Co., Ltd.

This firm was established as a fully-owned affiliate of Shionogi in January 2008 for contract testing of pharmaceuticals and other materials. Shionogi will expand contract laboratory service using testing techniques cultivated in its history.

  • Specification Testing and Stability Testing
  • Surface Analysis and Environmental Analysis

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